Arthritis sucks, no question about it. It's complicated by your other medical issues.

Have you looked at the Arthritis Foundation website? There is information there on supplements, etc. http://www.arthritis.org/living-with-arthritis/treatments/natural/

I take SAM-e as needed. It works as well as a low dose of Motrin and has no side effects for me. However, I take only one other medication daily and SAM-e doesn't interact with it. Your situation may be entirely different.

There is a new study showing modest benefit for hand OA for Chondroitin Sulfate.